Satratoxin G–Induced Apoptosis in PC-12 Neuronal Cells is Mediated by PKR and Caspase Independent
نویسندگان
چکیده
منابع مشابه
Satratoxin G-induced apoptosis in PC-12 neuronal cells is mediated by PKR and caspase independent.
Satratoxin G (SG) is a macrocyclic trichothecene mycotoxin produced by Stachybotrys chartarum, a mold suggested to play an etiologic role in damp building-related illnesses. Acute intranasal exposure of mice to SG specifically induces apoptosis in olfactory sensory neurons of the nose. The PC-12 rat pheochromocytoma cell model was used to elucidate potential mechanisms of SG-induced neuronal ce...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2008
ISSN: 1096-6080,1096-0929
DOI: 10.1093/toxsci/kfn110